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Vitamin B12's main functions are in the formation of red blood cells and the maintenence of a healthy nervous system. Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells and it aids in the production of DNA and RNA, the body's genetic material.
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Cyanocobalamin works to promote normal growth and development, helps with certain types of nerve damage, and treats pernicious anemia. Vitamin B12 helps in the formation of red blood cells and in the maintenance of the central nervous system. Nerves are surrounded by an insulating fatty sheath comprised of a complex protein called myelin. B12 plays a vital role in the metabolism of fatty acids essential for the maintenance of myelin. Prolonged B12 deficiency can lead to nerve degeneration and irreversible neurological damage.
Vitamin B12 is essential for the proper production of blood platelets and red and white blood cells, the manufacture of vital substances needed for cell function, and the metabolism of nutrients necessary for cell growth. It participates in a variety of cellular reactions to release energy from carbohydrates, fats and protein. Vitamin B12 helps maintain the myelin sheath that insulates nerve fibers from each other. People with Vitamin B12 deficiency show irregular destruction of the myelin sheaths, which eventually causes paralysis and death. Vitamin B12 levels decrease with age and various measures of cognitive impairment are associated with reduced B12 status. The most important use of Vitamin B12 is to treat the symptoms of pernicious anemia. Vitamin B9 (folate) and vitamin B12 are critical to the health of the nervous system and to a process that clears homocysteine from the blood. Vitamins B12, B-6, and B-9 (folate) work closely together to control blood levels of the amino acid homocysteine. Elevated plasma homocysteine concentrations are considered to be a risk factor for vascular disease and birth defects such as neural tube defects.
Vitamin B12 is a water-soluble vitamin that is stored in the liver. Vitamin B12 is a collective term for a group of cobalt-containing compounds known as corrinoids. The principal cobalamins are cyanocobalamin, hydroxocobalamin and the two coenzyme forms of Vitamin B12, methylcobalamin and 5-deoxyadenosylcobalamin (adenosylcobalamin). Cyanocobalamin is the principal form of the vitamin used for fortification of foods and in nutritional supplements. Vitamin B12 is also called cobalamin because it contains the metal cobalt. Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases B12 from proteins in foods during digestion. Hydroxocobalamin is a man-made form of Vitamin B12. The advantage using hydroxocobalamin is the lack of adverse effects seen with the nitrites such as methemoglobinemia and hypotension. It works by exchanging the hydroxy group for cyanide to form the non-toxic cyanocobalamin (Vitamin B12).
Use Vitamin B12 as directed by your doctor. Take Vitamin B12 by mouth with or without food. Ask your health care provider any questions you may have about how to Vitamin B12.
If you miss a dose of Vitamin B12 and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Store Vitamin B12 at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep Vitamin B12 out of the reach of children and away from pets.
Vitamin B12's main functions are in the formation of red blood cells and the maintenence of a healthy nervous system. Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells and it aids in the production of DNA and RNA, the body's genetic material.
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